a large descending neuron that drives escape behavior in flies
first described by Power 1948 with staining
characterized further by Levine and Tracey 1973
receives visual input from LPLC2 and then connects to tergal depressor of the trochanter (TDT) muscles
one of the original drawings of the giant fiber (GF) from power 1948:
references
Klapoetke.etal2017
Power, M. E. (1948). The thoracico‐abdominal nervous system of an adult insect, Drosophila melanogaster. Journal of Comparative Neurology, 88(3), 347–409. https://doi.org/10.1002/cne.900880303
Levine, J., & Tracey, D. (1973). Structure and function of the giant motorneuron ofDrosophila melanogaster. Journal of Comparative Physiology, 87(3), 213–235. https://doi.org/10.1007/BF00696043